Nutrition Assessment
- No single reliable biochemical marker.
- Poor prognosis:
- Unintentional weight loss >10% in 3 months
- (Cancer)
- Low albumin
- (Liver Cirrhosis)
- BMI <15
- (Malnutrition)
- Assessment methods:
- Fat: Skin fold thickness.
- Muscle mass: Mid arm circumference.
Malnutrition Universal Screening Tool (MUST)
- Assesses risk based on:
- BMI.
- Weight loss.
- Acute disease.
- Mnemonic: Must (MUST Tool) Lose (Weight loss) BMI () Fast (Acute)
Types of Nutrition
- Enteral (Oral/gut).
- Parenteral (IV route).
Enteral Nutrition
Benefits of Enteral Nutrition
- Better method.
- More physiological.
- Prevents translocation of gut bacteria.
Best Route
- Oral.
If oral not possible:
Requirement | Good gastric emptying | Poor gastric emptying |
<3 weeks | Nasogastric (NG) tube | Nasojejunal (NJ) tube |
>3 weeks | Feeding gastrostomy | Feeding Jejunostomy |
Benefits | More physiological. ↑ Risk of aspiration. | Bypasses stomach. |

Ryle's Tube (NG tube)

- Length assessment:
- Nose → Ear → Xiphoid.
- Patient position for insertion:
- Sitting with neck slightly flexed.
Check NG tube position by:
- Clinical methods:
- Aspirating gastric contents.
- Whoosh test:
- Pushing air F/B auscultation in epigastrium.
- Imaging:
- Chest x-ray
Techniques for Gastrostomy and Jejunostomy
Open Techniques

- a. Stamm method:
- Uses purse string suture.
- ↑ Chances of peri-drain leak.
- Mnemonic: Stamm → Stab → ↑↑ Leak
- b. Witzel technique:
- Creates a tunnel.
- ↓ peri-drain leak.
- Mnemonic: Witzel → Wizard tunnel ()
Percutaneous Endoscopic Gastrostomy (PEG)

- Method of insertion:
- Endoscope passed in stomach.
- Illuminated site palpated & punctured.
- PEG tube inserted over guide wire and secured.
- Introducer of PEG is part of the PEG set.
Radiologically Inserted Gastrostomy (RIG)
- Done when endoscopy is not possible.
Complications of Enteral Nutrition
- Tube related:
- Blockade.
- Migration.
- Leak.
- Feeding regime related:
- Osmotic diarrhoea (Sugar rich fluids).
- Overfeeding (↑Risk of aspiration).
Parenteral Nutrition
- Best Route
- Central line.
- Indications
- Prolonged paralytic ileus (>72 hours).
- Short bowel syndrome (<200 cm small intestine).
- High output faecal fistula (>500 cc/24 hours).
- Acute episodes of inflammatory bowel disease.
- Acute severe pancreatitis (initial phase only).

Central Line Types and Characteristics
Feature | Subclavian vein | Internal jugular vein | Femoral vein |
Risk of thrombosis & infection | Least | Intermediate | Maximum |
Risk of pneumothorax | Maximum | Intermediate | Least |
Ease of insertion | Medium | Maximum ease | Medium |
Other | M/c in TPN | M/c used vein overall | ㅤ |
Internal Jugular Vein – Preferred in
Condition / Requirement | Reason for Preferring Internal Jugular Vein |
Bleeding diathesis | Bleeding easily detected and controlled with pressure |
Pneumothorax risk | Lesser risk of lung injury |
Cardiac pacing | Right internal jugular vein is preferred |
Complication | Key Point / Association |
Arterial puncture | Most common complication |
Cardiac tamponade | Most important life-threatening; due to puncture of intrapericardial SVC, RA, or RV |
Pneumothorax | More common with subclavian vein catheterization |
Chylothorax | ㅤ |
Nerve injury | ㅤ |
Thromboembolism | ㅤ |
Infections | ㅤ |
Chylothorax
- L subclavian vein catheterization
- Lymphatic leaks
- Triglyceride > 110 mg/dl

Pseudo chylothorax
- Seen in RA
- Normal TG → Cholesterol crystals +
Post-Insertion Check

- Chest x-ray:
- Look for central line tip.
- Rule out pneumothorax.
- Catheter tip position:
- In SVC.
- Just above the Rt atrium.
PICC line (Peripherally Inserted Central Catheter).
- Just above the Rt atrium.
TPN solution

- Contents: Lacks fibre content.
- Protein : Fat : Carbohydrate
- = 20 : 30 : 50.
- Infusion rate: 1-2 litres/24 hours.
TPN solution modifications:
- Respiratory failure:
- ↓ Carbohydrate (Osmolar).
- ↑↑ Carbohydrate → ↑ CO2
- ↓ Quantity.
- Renal failure:
- ↑ Carbohydrate.
- Less Protein (d/t creatinine)
- ↓ Quantity.
Monitoring of Patients on Feeding Regimes
- Daily (Clinical measures):
- Pulse, BP, Temperature.
- Body weight (↑: earliest sign of overfeeding).
- Input/output chart.
- Type of nutrition given.
- Biochemical measures
- (Initially daily, then later once/twice a week):
- Blood glucose.
- Magnesium, Phosphate.
- Liver function tests.
- RFT
- Sodium, Potassium, Urea, Creatinine.
- C-reactive protein.
Complications of TPN
- Central line related:
- Pneumothorax.
- Arrhythmias, Thrombosis, Air embolism.
- Migration.
- Catheter related sepsis (m/c central line complication).
- Feeding regime related:
- Hyperglycemia (m/c).
- Excess weight gain.
- Cholestasis (withhold TPN).
- Micronutrient deficiency (m/c: Zinc deficiency).
- Refeeding syndrome.
Catheter Related Sepsis
- On fluid administration: Fever + chills & rigors.
- Investigation:
- Cultures from:
- Catheter tip.
- Peripheral line.
- Central line.
- Management:
- Remove catheter if it is the source.
Refeeding Syndrome
- Large quantities of nutrition given to chronically malnourished.
- Main cause of death:
- Congestive heart failure
- Arrhythmias
- Metabolic derangements:
- ↓ PO4+ (main driver).
- ↓K+, ↓Ca2+, ↓Mg2+.
- Mnemonic: PAPPM
- Fluid overload.
- Patient at risk:
- BMI <16 kg/m3 .
- Unintentional weight loss >15% within last 3-6 months (≥1 factor).
- Little/no nutrition intake for >10 days.
- ↓K+, ↓PO4+, ↓Mg+ prior to feeding.
- Prevention:
- ↑ Feeds gradually
- initially 10 kcal/kg/day
- Full feeds in 4-7 days
- Strict electrolyte levels monitoring.
- Thiamine supplementation.
Change | Mechanism |
↓ PO₄³⁻ | Insulin drives phosphate into cells; For ATP & 2,3-BPG |
↓ K⁺ | Insulin-mediated uptake |
↓ Mg²⁺ | Shift into cells; |
↓ Thiamine (B1) | d/t ↑↑ carbohydrate metabolism |
Liver Dysfunction in TPN
- Long term TPN use leads to Fatty liver (m/c).
- Children (m/c).
- Can be modified using lipid free solutions.
- Intestinal Failure Associated Liver Disease (IFALD):
- Occurs in small number of patients.
Hartmann's/Ringer Lactate (RL) Solution
Composition (in meq/L):
- Lactate → Always Ringer Lactate
Parameter | Value | ㅤ |
Na⁺ | 131 | 131 → normal level |
Cl⁻ | 111 | 1 → 111 |
K⁺ | 5 | 5 → normal level |
Ca²⁺ | 2 | 2 → 2 |
Lactate | 29 | ㅤ |
ORS Contents
Component | Standard (mEq/L) | Reduced Osmolarity (mmol/L) |
Glucose | 111 | 75 |
Sodium | 90 | 75 |
Chloride | 80 | 65 |
Potassium | 20 | 20 |
Citrate | 10 | 10 |
Osmolarity | 311 | 245 mOsm/L |
ㅤ | ㅤ | Sodium (75) chloride (65) Potassium (20) Citrate (10) |
Reduced Osmolarity ORS Ingredients (g per 1L)
Component | g/L |
Glucose (anhydrous) | 13.5 |
Trisodium citrate hydrate | 2.9 |
Sodium chloride | 2.6 |
Potassium chloride | 1.5 |
Total | 20.5 g |
- Use 1 packet in 1L water.
- Consume within 24 hours.
Special ORS Types
- Resomal (for malnourished): Na 45, K 40
- For SAM children
- Not freely available (costly)
- more potassium
- less sodium
- some minerals.
- Super ORS:
- Uses rice/non-starch sugars (glycine, alanine)
- Low shelf life

Which and how much maintenance fluid to use?
- In children
- NS with 5% dextrose
- + 1 ml KCl/100 ml
- (20 meq/L of K+)
- 1 mL KCl = 2 meq KCL
- For 1st 10 kg:
- 100 ml/kg
- Next 10 kg:
- 50 ml/kg
- Beyond 20 kg:
- 20 ml/kg
- Example:
- Weight of child = 18kg
- For 1st 10kg = 10x100=1000ml
- For next 8kg = 8x50=400ml
- So, child needs 1400 ml of IV fluid in 24 hours