Kidney surgical conditions😍

Duplication of Ureteric System/ Duplex ureter

notion image

Weigert-Meyer Rule:

  • Upper pole ureter:
    • Ectopic insertion.
    • Inferomedial to normal.
  • Middle/lower pole ureter:
    • Normal insertion.
notion image

Ectopic Sites:

  • Male: Urethra.
  • Female: Vagina (causes urinary dribbling).

Investigation:

notion image
  • Intravenous Urogram (IVU):
    • Urograffin dye used.
      • notion image
  • "Drooping Lily" sign
    • (duplication + pelvic malrotation).
    • Mnemonic: Droop → Dupe
      • notion image

Management:

  • Ureter reimplantation.

Horseshoe Kidney

notion image
notion image
 
 
notion image
 

Features:

  • M > F (2:1)
  • Lower poles of both kidneys are fused.
  • Located at L3-L4 level.
  • Ascent restricted by inferior mesenteric artery.
  • Adrenal glands are in normal position (separate embryology).

Investigation:

  • Known as joining hands or handshake or flower vase appearance
    • Has association with Turner's syndrome.
    • IVU: "Flower Vase" or "Hand Shake" sign.
    • Fuse at isthmus
    • Inferior mesenteric ArteryAnterior to isthmusPrevent ascent
      • notion image
        IVU
        IVU

Complications

  • ↑ Risk of RCC, Wilms Tumor, Multicystic dysplastic kidney
  • UTI
  • Nephrolithiasis/Hydronephrosis

Management:

  • Pyeloplasty: If hydronephrosis/malrotated pelvis.
  • Avoid cutting the fused portion due to devascularization risk.

Polycystic Kidney Disease (PCKD)

notion image
notion image

PRESENTATION

  • HEMATURIA+ HYPERTENSION +LOIN/ FLANK PAIN ( IMP)
  • Gross haematuria following trauma → due to cyst rupture.

Types:

Feature
ADPKD
Autosomal Recessive Polycystic Kidney Disease (ARPKD)
Prognosis
Adult
Infantile → Fatal
Chromosomes
PKD1 (Chromosome 16)
PKD2 (Chromosome 4)
PKHD1 (Chromosome 6)
Gene
PKD gene
PKHD gene
Protein
Polycystin
Fibrocystin
Cyst Appearance
Cysts on both outer and inner surfaces of kidney.
Only inner surface shows cysts; outer surface normal.
Associated Organs
ABCD
Aortic aneurysms/dissections
Berry aneurysms
Cysts in pancreas/liver
Colonic Diverticula
Congenital hepatic fibrosis 
(H for hepatic, fibro for fibrosis).
Clinical Presentation
More common in males.

Clinical Features:
Hypertension (M/c, in 3rd decade).
Abdominal mass, hematuria, multiple cysts.
• Berry aneurysm

Cyst size↑↑ →
Symptomatic
  • Extrarenal Manifestations:
    • Most common: Liver cysts.
    • Cysts in spleen, pancreas, lungs.
    • Colonic diverticulosis.
    • Mitral valve prolapse.
    • Berry aneurysms in Circle of Willis (can cause subarachnoid hemorrhage).

Investigation:

  • Ultrasound (can be prenatal).

Xray

notion image
notion image

ADPKD

  • On CT scan (Image 1), white bone is observed.
    • Both kidneys are enlarged in size and have multiple cysts.
  • On MRI (Image 2), black bone is observed.
    • Both enlarged kidneys have multiple cysts.
  • In IVP, initial or nephrogram phase:
    • Multiple cysts do not take up the contrast,
    • forming filling defects in the kidney.
  • Spider leg appearance.
    • d/t Splayed collecting system
      • notion image
  • Swiss cheese appearance
    • On nephrogram
notion image

ARPKD

  • Striated appearance or sunray appearance of the kidneys.
  • The kidney appears echogenic on ultrasonography.

Management:

  • Transplant.
  • Dialysis.
  • Note: Cyst deroofing surgery not used.

Renal Cysts

notion image

Bosniak Classification for Renal Cysts

  • Bosniak classification is used to group renal cysts based on malignancy risk.
notion image
notion image
Class
Description
Work up
% Risk of malignancy
1
Simple cyst
Nil
0%
2
Minimally complex
Nil
0%
2F
Minimally complex
USG/CT follow up
5%
3
Indeterminate
Partial nephrectomy
50%
4
Clearly malignant
Partial/Total nephrectomy
100%
  • Anandhu → Bose now → has Renal cyst
notion image

Hydronephrosis

Features:

  • Aseptic dilation of the pelvicalyceal system.

Hydronephrosis

  • Left kidney
    • gray color density → fluid.
    • Enhancing rimrenal parenchyma.
      • Rim sign seen in hydronephrosis.
        • notion image
notion image

Unilateral Causes:

Intraluminal:

  • Stone disease (most common acquired cause).
  • Sloughed papillae.

Intramural:

notion image

PUJ obstruction:

notion image
notion image
  • Most common congenital cause.
  • Adynamic obstruction → No physical obstruction → but PUJ is not contracting
  • IVU: Clubbing of calyces.
  • Surgery: Anderson-Hynes Pyeloplasty.
  • Mnemonic: Anangatha (Adynamic) Andi Poya (Anderson Pyeloplasty) Pug (PUJ) → Club (clubbing) il cherth

Ureterocele:

notion image
  • IVU: "Cobra Head" or "Adder Head" sign.
  • Cystic dilatation of ureteric terminal end.
  • Surgery: Ureter reimplantation.

Transitional cell carcinoma (pelvis/ureter):

  • "Goblet sign" on IVU.

Extraluminal:

  • Aberrant renal vessel
    • usually unilateral,
    • never cut,
    • manage with pyeloplasty
  • Advanced cancers (colorectal, cervical, prostate).

Retroperitoneal fibrosis (Ormond's disease)

notion image
notion image
  • Can compress uretershydronephrosis
  • "Maiden Waist" deformity, medial indrawing of ureters.
  • Causes:
    • Idiopathic
    • post-radiotherapy
    • drug-induced (Methysergide).
  • Management: DJ Stenting.
  • Mnemonic: Purakil ninn (retroperioneal) DJ () kalikkunna Maid () ne Ormayundo (Ormond)

Retrocaval ureter:

notion image
  • Right ureter passes behind IVC.
  • Hydronephrosis + hydroureter (of the proximal ureter)
  • "Reversed J" or "FishHook" sign.

Bilateral Causes:

  • Any unilateral cause on both sides.
  • Benign Prostatic Hyperplasia (BPH).
  • Bladder outlet obstruction (e.g., urethral stricture).
  • Posterior urethral valves.
  • Phimosis.
  • Meatal stenosis.

Investigations:

  • IVU: Clubbing of calyces.

Renal Scans

  • Technetium-99m
  • DMSA:
    • Mnemonic: Morphology → Scar → Static
    • Used for kidney scars or morphological changes.
    • Detects if the kidney is located ectopically.
    • It is a static scan.
    • no GFR or tubular function
  • DTPA:
    • Gives the function/physiology of the kidney (GFR).
  • MAG3:
    • Mnemonic: Magnificient
    • Helps in evaluating GFR and tubular function.

Whitaker Test – Used to differentiate between obstructive vs non-obstructive hydronephrosis

Principle:

  • Measures differential pressure between the renal pelvis and bladder during fluid infusion.

Procedure:

  • A percutaneous nephrostomy is created (puncture through loin into the renal pelvis).
  • Normal saline or contrast is infused at a constant rate (typically 10 mL/min) into the renal pelvis.
  • Simultaneous measurement of pressure in:
    • Renal pelvis
    • Bladder

Interpretation:

  • Normal: Renal pelvic pressure stays <22 cm H₂O.
  • Obstruction:
    • Renal pelvic pressure >22–25 cm H₂O, or a
    • pressure gradient >15 cm H₂O between renal pelvis and bladder.
  • While taking water (Whitaker)

Uroflowmetry

notion image
  • >15 ml/sec: Normal.
  • 10-15 ml/sec: Equivocal.
  • <10 ml/sec: Low flow.

Christmas or pine or fir tree appearance

  • Seen in neurogenic bladder.
  • The tone of the bladder is affected, causing a shape change from round to elongated.
  • Multiple diverticuli are present.
    • notion image
      notion image

Teardrop or pear shape or inverted pear shape appearance

notion image
  • In an IVP image, the bladder appears to have a teardrop shape.
  • A normal bladder is compressed by external forces, causing elongation.
  • Causes include:
    • Extrinsic compression of the bladder.
    • Any pelvic cause.
      • e.g., pelvic lipomatosis, pelvic abscess, pelvic hematoma, pelvic lymphadenopathy, pelvic vessel aneurysm.

Fetal skull calcification of the urinary bladder

notion image
notion image
  • Seen in schistosomiasis.
  • Bladder wall calcification
  • Schistosoma haematobium resides in the vesical venous plexus of the bladder.

Renal Stones

Types

notion image
notion image
notion image
notion image
notion image
Crystal Type
Shape
Associated With
Mnemonic / Notes
Tyrosine
Very thin needles
"Tyrosine → inject insulin → thin needle"
Bilirubin
Thin pigmented 
(golden-brown) needles
Ammonium Biurate
Apple-thorn
Laxative abuse
Leucine
Lamellated (like tree bark)
Leucine → Lamelle
Cholesterol
Broken chips
"chips rich in cholesterol"
Calcium Carbonate
Round like car wheels
"carbonate, car wheels"

Calcium Oxalate:

notion image
  • Most common type.
  • Radio-opaque.
  • Formed in acidic urine.
  • Monohydrate:
    • Most common
    • Dumbbell-shaped, very hard.
    • SIngles use dumbell
  • Dihydrate:
    • Envelope-shaped, spiculated ("Mulberry" stones),
    • present early with pain/hematuria
    • Doubles → send letters → envelope

Triple Phosphate (Struvite/Staghorn):

notion image
notion image
  • Calcium Ammonium Magnesium Phosphate.
  • Associated with
    • Proteus urinary tract infection.
    • Parathyroid adenoma Hypercalcemia Calcium deposits in kidney
  • Radio-opaque.
  • "Coffin Lid" shaped.
  • Formed in alkaline urine.
  • Features
    • Smooth surface, large size.
    • takes up the shape of the pelvis and calyces.
    • Calcification with lobulated appearance, i.e. parenchymal
  • Coffin lu avathirikkan Maaninte (Staghorn) irachi thinnanam + Protein (Proteus) thinnanam→ Strong (Struvite) avanam
  • DMSA scan for scarring.
Condition
IOC
Features
Stag Horn Calculus
plain x-ray.
PUJ Obstruction
IVP
Non-visualization of the ureter
hydronephrosis without hydroureter
affected kidney is dilated → hydronephrosis
affected ureter is not seen →
PUJ obstruction
VUR
MCU / VCUG
notion image
notion image

Cystine:

notion image
  • "six as cis"
 
  • Radio-opaque.
  • Very hard (crystalline lattice).
  • Hexagonal shape.
  • Difficult to break by ESWL.
  • Seen in cystinuria.
    • COLA tin (cystin-uria) lost in urine
      • Cystine
      • Ornithine
      • Lysine
      • Arginine
  • Management for recurrent stones: d-Penicillamine.

Uric Acid:

notion image
notion image
  • Most common radiolucent stones.
  • "Glass Shreds" crystals.
  • ‘’Rhomboid’’ shape
  • Seen in tumor lysis syndrome, gout.
  • Uric acid → Universal shapes (triangular, diamond, random)
  • Rx: Alkalinization of urine

Radiolucent

  • Xanthine
  • Orotic acid
  • Urea stone
  • Triamterene
  • Indinavir (from anti-retroviral treatment).
  • Xanthaclose (Xanthine) Urine (Uric acid) is Loose (lUcent)

Rare Stones:

notion image

Presentation

  • Pain (Most common):
    • Colicky pain (depends on stone site):
      • Pelvis: Loin to groin radiation.
      • Upper/mid ureter: Iliohypogastric nerve.
      • Lower ureter: Ilioinguinal nerve.
      • Impacted intramural portion: Strangury (intense urge with bloody drops).
    • Fixed renal pain: At renal angle.
  • Hematuria.
  • Hydronephrosis.
  • Dietl's Crisis:
    • Stone blocks urine flow -> pain + palpable mass.
    • Stone shifts -> large quantities of dilute urine.

Investigations

  • CT Urography (also Radiolucent) >> Non-contrast CT (NCCT)
  • Partial vs complete obstruction: Diuretic DTPA scan

Ureteric calculi

  • Ureteric stone is generally vertically oval.
    • notion image

Renal Calculus

  • A white area (right kidney) → right renal calculus
    • Right kidney + psoas major muscle located posteromedially.
      • notion image
  • On ultrasound → echogenic area + shadow behind it.
    • Shadow → posterior acoustic shadowing.
      • notion image
notion image

B/L Nephrocalcinosis/ Medullary Nephrocalcinosis

  • Lucent areas are observed between opaque areas.
  • 2 causes
    • A/w Hyperparathyroidism
    • Medullary sponge kidney
  • Functional kidney
    • notion image

Medullary sponge kidney appearance in IVP

  • Paintbrush or bouquet of flowers appearance.
  • Dilated collecting ducts / medullary ducts (Bellini ducts)
  • A/w nephrocalcinosis and recurrent renal stones
    • notion image

Management

  • Dietary Advice (recurrent calcium oxalate stones):
    • Decrease fat content.
    • Increase calcium intake.
    • Increase pyridoxine dose.
    • Cholestyramine: Binds oxalate in gut.

Based on stone size:

notion image
  • < 5mm:
    • No active intervention.
  • 5 - 1.5 mm, symptomatic:
    • Medical management (1st line).
      • Tamsulosin (alpha blocker):
        • Relaxes distal ureteric muscle.
      • Fail → ESWL
  • > 2 cm:
    • PCNL (Percutaneous Nephrolithotomy).

Extracorporeal Shock Wave Lithotripsy (ESWL):

notion image
notion image
  • Complications:
    • "Stone street" (Stein strasse),
    • pain (most common),
    • hematuria,
    • UTI.
  • Ultrasonic waves fragment stone.
  • Contraindications:
    • Pregnancy,
    • uncontrolled bleeding disorder,
    • cardiac pacemaker.
    • Stone > 1.5 cm.
    • Children,
    • obese patients.
    • Very hard stones (Cystine > Calcium Oxalate Monohydrate).
    • Obstructed system.
    • Lower calyx stone.

Percutaneous Nephrolithotomy (PCNL):

notion image
  • Indications:
    • Stones > 2 cm
    • lower pole stones unfavorable for SWL
    • failed ESWL/RIRS,
    • staghorn calculi.
    • Cystine, Calcium Oxalate Monohydrate
  • Mini PCNL:
    • For children, tracks < 22F.
    •  

Retrograde Intrarenal Surgery (RIRS):

notion image
  • Indications:
    • Stones < 2 cm,
    • lower pole,
    • obesity,
    • musculoskeletal deformities.
    •  
notion image

Ureteroscopic Removal of Stones (URS):

notion image
  • Dormia basket:
    • To capture stones.
      • notion image
  • Bilateral Double J (DJ) stents:
    • Facilitate passage of stone fragments,
    • inserted via cystourethroscope.
      • notion image

Bladder Stones

notion image
notion image
notion image

Features:

  • Most common in children.
  • Most common type: Mixed urate.

NCCT

  • Dense calcification in the center of the pelvis is observed.
  • This is the bladder stone or vesical calculus.
    • notion image

Management:

  • 1st line:
    • Perurethral cystolithotomy.
  • If contraindicated
    • d/t urethral stricture, bladder diverticulae
      • Suprapubic cystolithotomy.

Vesicoureteral Reflux (VUR)

notion image

Grades (reflux severity):

notion image
notion image
Grade
Description
Grade 1
Into non-dilated ureter
Grade 2
Into renal pelvis, no distension
Grade 3
Mild distension
Grade 4
Blunting of calyces,
tortuous ureter
Grade 5
Severe distension,
loss of papillary impressions
 
notion image

Investigation:

  • Micturating Cystourethrogram (MCU).
    • notion image
  • DMSA scan for scarring.
Condition
IOC
Features
Stag Horn Calculus
plain x-ray.
PUJ Obstruction
IVP
Non-visualization of the ureter
hydronephrosis without hydroureter
affected kidney is dilated → hydronephrosis
affected ureter is not seen →
PUJ obstruction
VUR
MCU / VCUG
notion image
notion image

Treatment (due to recurrent UTIs):

  • Supportive
    • VUR resolves spontaneously
    • Adequate fluids.
  • Grades 1-5:
    • Prophylactic antibiotics.
    • Drugs : Cotrimoxazole/nitrofurantoin/Cephalexin.
    • Regimen : Until 2 years of age + 1 year after last episode of UT.
  • If no recovery for Grade 4, 5:
    • STING procedure (Sub-Ureteric Teflon Injection).
      • notion image

Posterior Urethral Valve (PUV)

  • Primary reason for bladder outlet obstruction in male children

Young's Classification

Type
Feature
Type 1 (M/c)
Anteroinferior to verumontanum.
Type 2
rare
Type 3 (Cobb’s collar).
rare

Clinical Features

  • Male child with recurrent UTI.
  • A/w Oligohydramnios

Imaging in PUV

notion image
  • USG
    • "Keyhole sign"
      • notion image
  • MCU → IOC
    • notion image
  • Management: Fulguration of the valve.

Renal artery stenosis

notion image
notion image
  • Affects the ostium.
  • Young patient (without a family history of hypertension)
  • 1st investigation is renal Doppler (Image 1)
    • has a slow and blunted uptake.
      • i.e. pulsus parvus et tardus waveform (Image 2)
    • Normal renal artery has a quick upstroke.
  • 2nd investigation is CT-angiography or MR-angiography.
  • Gold standard procedure is digital subtraction angiography (DSA).

Fibromuscular dysplasia

  • Beaded appearance.
  • Seen in an MR-angiography.
  • Indicates multiple strictures in the renal artery.
  • Common in young adult females.
  • Also presents with hypertension (similar to renal artery stenosis).
    • notion image
       
      notion image

Ectopia Vesica (Bladder Extrophy)

  • Anterior abdominal wall and anterior bladder wall
    • deficient below the umbilicus.
notion image

Clinical Features

  • ADENO CA BLADDER
  • EPISPADIA
  • Urine dribbling from bladder.
  • Undescended testis.
  • Bifid clitoris.
  • Pubic diastasis.
 

Urethra

notion image
notion image

Length

  • Female: 3-4 cm.
  • Male: 18-21 cm.

Parts

  • Proximal: Membranous + Prostatic Urethra.
  • Distal: Penile + Bulbar Urethra.

Epithelium of Male Urethra

Part
Notes
Pre-prostatic &
Prostatic urethra
Transitional epithelium
Membranous urethra
Pseudostratified / Stratified columnar
Bulbar urethra
Most distensible part
Penile (Spongy) urethra
• Proximal → Pseudostratified columnar
• Distal →
Stratified squamous

Transitional epithelium / urothelium lines

  • Renal pelvis and calyces,
  • ureter
  • urinary bladder
  • pre-prostatic & prostatic parts of the urethra
notion image
notion image
notion image
notion image

Hypospadias

Features

  • Most common congenital urogenital anomaly.
  • Ventrally placed urethral opening.
  • Associated with micropenis & undescended testis.

Types

notion image
notion image
  • Most common & mildest:
    • Glanular.
  • Most severe:
    • Perineal.

Clinical Features

  • Downward-directed urine stream.
  • Downward bending of penis (Chordee).
  • Infertility.
  • Micropenis
  • H/o undescended testis
  • On Examination:
    • Urethral opening on the lower aspect.
    • Hooded prepuce.

Hypospadias Management

Steps of Surgery: 

  • Orthoplasty Urethroplasty Meatoplasty Glanuloplasty Skin cover.
  • Mnemonic: OUMG / OUGM

Surgical Procedures:

  • Single Stage:
    • Distal hypospadias:
      • Mustardee, Mathieu.
    • Mid hypospadias:
      • Snodgrass, TIP.
    • Mnemonic:
      • Mastard mathai (Mustard mathieu) → does sex in single stage () → with his small grass tip (Snodgrass, TIP)
  • Double Staged:
    • For proximal hypospadias.
      • Thiersch-Duplay,
      • Dennis Brown.
    • Mnemonic:
      • Does sex in 2 stage () → Foreplay (Duplay) and brown dick (Dennis brown)

Renal Tuberculosis

Features:

  • Secondary infection (hematogenous spread).

Presentations:

notion image
notion image
notion image

Renal

notion image
  • Papillary UlcersGhost calyx/Pseudo calculiCaseous necrosisPus filled kidneyCalcification ("Putty" or "Cement" kidney).

Ureter

notion image
  • Kirrs Kink
    • Bending of ureter
  • Shortening of ureter
  • Golf hole ureteric orifice
    • Orifice remain open
  • Pale ureteric orifice
    • Indicates inflammation and edema of surrounding mucosa
    • Early sign

Clinical Features:

  • Hematuria, pain, mass, weight loss.
notion image

Putty kidney

notion image
notion image
  • Cement (amorphous calcification) + lobulated appearance = parenchymal calcification
  • Moth eaten calyces
    • Earliest sign in the IVP for renal TB
    • irregularity of the calyx.
  • Later stages of TB
  • non-functional kidney and auto-nephrectomy.
  • Sterile pyuria is seen in urinary TB.

Corkscrew and Beaded appearance

  • Multiple ureteric strictures
    • notion image

Thimble bladder

notion image
notion image
  • small, contracted bladder
  • Heal with fibrosis
    • bladder wall calcification

Investigations:

  • Urine examination: Sterile pyuria (pus cells +, culture -).
  • Confirmatory:
    • ZN Staining of centrifuged 3 morning urine samples.

Note:

  • If genital TB
    • Genital swab for polymerase chain reaction (PCR) testing

Treatment:

  • Medical: Anti-tubercular treatment (ATT).
  • Surgical (for complications):
    • Perinephric abscess:
      • Drainage.
        • notion image
    • Ureteric kinking:
      • DJ stenting.
    • "Golf Hole" ureteric orifice:
      • Ureteric reimplantation.
    • "Thimble Bladder":
      • Augmentation cystoplasty.
    • Lower ureter damage:
      • Boari flap repair.
        • notion image

Pyelonephritis

Emphysematous Pyelonephritis:

notion image
notion image
  • Black areas
    • Air is contained within the kidney and surrounding it.
  • Organism: E.coli.
    • Note: clostridium → emphysematous cholecystitis
  • Common in immunocompromised, DM patients.
  • Can turn fulminant and septic.
  • IOC: CECT (gas in/around kidney).
  • Management: Antibiotics + drainage.

Xanthogranulomatous Pyelonephritis:

notion image
  • IOC: CECT
    • non-functioning kidney,
    • calculi,
    • low-density masses
  • Proteus.
  • Common in middle-aged females with DM.
  • Symptoms: Flank pain, pyrexia, abdominal mass.
  • Management: Nephrectomy (subcapsular if management fails).

Acute pyelonephritis

  • In acute pyelonephritis, the kidney is enlarged.
  • In chronic pyelonephritis, the kidney is shrunken.
  • Enlarged edematous kidney → Total / Focal
  • A striated appearance is observed.
  • Reduced areas of cortical vascularity on power Doppler
    • notion image

Renal Papillary Necrosis

  • Signet ring appearance.
  • Contrast is seen around the necrosed papilla.
    • notion image

Chronic Pyelonephritis

notion image
notion image
  • CauseE. coli.
  • Gross appearanceAsymmetrically contracted kidney.
  • Urine microscopyWBC cast.

Histopathological Features Chronic Pyelonephritis

notion image
  • Atrophy of tubules → Lymphocytic infiltrate.
  • Flattened epithelium.
  • Thyroidization of tubules.
  • Periglomerular fibrosis.