URINARY TRACT IMAGING
Contrast X-rays

Dye studies for urethra | Route |
IVP | Intravenous Pyelogram • via IV • Urethra is not seen |
RGP | Retrograde Pyelogram • from down upwards • No bladder distension • view Ureter/Renal Pelvis |
RGU | Retrograde Urethrogram • Preferred for anterior urethra evaluation for strictures. • e.g., urethral strictures, urethral injury/rupture. |
MCU / VCUG | Micturating Cystourethrogram / Voiding cystourethrogram • 300ml contrast via foleys cannulation • Distend the bladder with contrast • IOC for 1. VUR 2. PUV |
Computed Topography (CT) Scans


CT Scans | Identify | ă…¤ |
CT-IVU or CT-IVP. | KUB + White bone | Colourful imaging can be produced from urine. |
T2 Magnetic Resonance (MR). | KUB NO White bone | Advantages 1. without contrast → Urine appears white 2. Safe in renal failure |
Urolithiasis
- The best investigation for Urinary tract calculi is CT since they are calcified.
- CT Urography (also Radiolucent) >> Non-contrast CT (NCCT)
- Partial vs complete obstruction: Diuretic DTPA scan
Ureteric calculi
- Ureteric stone is generally vertically oval.

Renal Calculus
- A white area (right kidney) → right renal calculus
- Right kidney + psoas major muscle located posteromedially.

- On ultrasound → echogenic area + shadow behind it.
- Shadow → posterior acoustic shadowing.

Vesicle calculus
- Dense calcification in the center of the pelvis is observed.
- This is the bladder stone or vesical calculus.

Hydronephrosis
- Left kidney
- gray color density → fluid.
- Enhancing rim → renal parenchyma.
- Rim sign seen in hydronephrosis.


Stag horn calculus


- Calcium Ammonium Magnesium Phosphate.
- Associated with
- Proteus urinary tract infection.
- Parathyroid adenoma → Hypercalcemia → Calcium deposits in kidney
- Radio-opaque.
- "Coffin Lid" shaped.
- Formed in alkaline urine.
- Features
- Smooth surface, large size.
- takes up the shape of the pelvis and calyces.
- Calcification with lobulated appearance, i.e. parenchymal
- Coffin lu avathirikkan Maaninte (Staghorn) irachi thinnanam + Protein (Proteus) thinnanam→ Strong (Struvite) avanam

Putty kidney


- Cement (amorphous calcification) + lobulated appearance = parenchymal calcification
- Moth eaten calyces
- Earliest sign in the IVP for renal TB
- irregularity of the calyx.
- Later stages of TB
- → non-functional kidney and auto-nephrectomy.
- Sterile pyuria is seen in urinary TB.
Corkscrew and Beaded appearance
- Multiple ureteric strictures

Thimble bladder


- small, contracted bladder
- Heal with fibrosis
- bladder wall calcification
Investigations:
- Urine examination: Sterile pyuria (pus cells +, culture -).
- Confirmatory:
- ZN Staining of centrifuged 3 morning urine samples.
Note:
- If genital TB
- Genital swab for polymerase chain reaction (PCR) testing

B/L Nephrocalcinosis/ Medullary Nephrocalcinosis
- Lucent areas are observed between opaque areas.
- 2 causes
- A/w Hyperparathyroidism
- Medullary sponge kidney
- Functional kidney

Differentiating Stag Horn Calculus, PUJ Obstruction and VUR
- DMSA scan for scarring.
Condition | IOC | Features |
Stag Horn Calculus | plain x-ray. | ă…¤ |
PUJ Obstruction | IVP | Non-visualization of the ureter hydronephrosis without hydroureter affected kidney is dilated → hydronephrosis affected ureter is not seen → PUJ obstruction |
VUR | MCU / VCUG | ă…¤ |


Popcorn calcification
- Popcorn calcification is observed in the pelvis.
- It is incomplete calcification.
- In post-menopausal females
- calcific degeneration of uterine fibroid.

Pyelonephritis
- Symptoms include fever, dysuria, and flank pain.
Acute pyelonephritis
- In acute pyelonephritis, the kidney is enlarged.
- In chronic pyelonephritis, the kidney is shrunken.
- Enlarged edematous kidney → Total / Focal
- A striated appearance is observed.
- Reduced areas of cortical vascularity on power Doppler

Emphysematous pyelonephritis


- Black areas
- Air is contained within the kidney and surrounding it.
- Organism: E.coli.
- Note: clostridium → emphysematous cholecystitis
- Common in immunocompromised, DM patients.
- Can turn fulminant and septic.
- IOC: CECT (gas in/around kidney).
- Management: Antibiotics + drainage.
Tuberculosis (TB) of the Urinary Tract
- TB causes destruction and fibrosis.
- The is the moth-eaten calyx.
- This suggests the

Putty kidney


- Cement (amorphous calcification) + lobulated appearance = parenchymal calcification
- Moth eaten calyces
- Earliest sign in the IVP for renal TB
- irregularity of the calyx.
- Later stages of TB
- → non-functional kidney and auto-nephrectomy.
- Sterile pyuria is seen in urinary TB.
Corkscrew and Beaded appearance
- Multiple ureteric strictures

Thimble bladder


- small, contracted bladder
- Heal with fibrosis
- bladder wall calcification
Investigations:
- Urine examination: Sterile pyuria (pus cells +, culture -).
- Confirmatory:
- ZN Staining of centrifuged 3 morning urine samples.
Note:
- If genital TB
- Genital swab for polymerase chain reaction (PCR) testing
Ureter Appearances
Ureterocele:

- IVU: "Cobra Head" or "Adder Head" sign.
- Cystic dilatation of ureteric terminal end.
- Surgery: Ureter reimplantation.
Duplication or Duplex moiety

Ectopic Sites:
- Male: Urethra.
- Female: Vagina (causes urinary dribbling).
Investigation:

- Intravenous Urogram (IVU):
- Urograffin dye used.

- "Drooping Lily" sign
- (duplication + pelvic malrotation).
- Mnemonic: Droop → Dupe

Management:
- Ureter reimplantation.
Medullary sponge kidney appearance in IVP
- Paintbrush or bouquet of flowers appearance.
- Dilated collecting ducts / medullary ducts (Bellini ducts)
- A/w nephrocalcinosis and recurrent renal stones

PCKD (AD) (Autosomal dominant polycystic kidney disease)
- The renal calyces are separated by the cysts.
Retroperitoneal fibrosis (Ormond's disease)


- Can compress ureters → hydronephrosis
- "Maiden Waist" deformity, medial indrawing of ureters.
- Causes:
- Idiopathic
- post-radiotherapy
- drug-induced (Methysergide).
- Management: DJ Stenting.
- Mnemonic: Purakil ninn (retroperioneal) DJ () kalikkunna Maid () ne Ormayundo (Ormond)
Horseshoe Kidney
- Known as joining hands or handshake or flower vase appearance
- Has association with Turner's syndrome.
- IVU: "Flower Vase" or "Hand Shake" sign.
- Fuse at isthmus
- Inferior mesenteric Artery → Anterior to isthmus → Prevent ascent


Retrocaval ureter:

- Right ureter passes behind IVC.
- Hydronephrosis + hydroureter (of the proximal ureter)
- "Reversed J" or "FishHook" sign.
Bladder Appearances
Christmas or pine or fir tree appearance
- Seen in neurogenic bladder.
- The tone of the bladder is affected, causing a shape change from round to elongated.
- Multiple diverticuli are present.


Teardrop or pear shape or inverted pear shape appearance

- In an IVP image, the bladder appears to have a teardrop shape.
- A normal bladder is compressed by external forces, causing elongation.
- Causes include:
- Extrinsic compression of the bladder.
- Any pelvic cause.
- e.g., pelvic lipomatosis, pelvic abscess, pelvic hematoma, pelvic lymphadenopathy, pelvic vessel aneurysm.
Fetal skull calcification of the urinary bladder


- Seen in schistosomiasis.
- Bladder wall calcification
- Schistosoma haematobium resides in the vesical venous plexus of the bladder.
Urethral Pathology
Urethral rupture
ă…¤ | Anterior Urethral Injury | Posterior Urethral Injury |
Injured Part | • Penile/bulbar urethra | • Membranous/ prostatic urethra |
Mode of Injury | • Direct trauma/straddle injury | • Secondary to pelvic fracture |
Features | • Superficial perineal hematoma • around penis/scrotum | • Deep perineal hematoma, • Vermooten sign (Floating prostate) |
- Contrast flows out of the urethra.


Bladder Rupture





Type | Extraperitoneal rupture | Intraperitoneal rupture |
ă…¤ | (more common) | ă…¤ |
Sign | molar tooth sign. | Contrast in paracolic gutters and inter-bowel loops area |
Secondary to | pelvic fracture. | blunt/penetrating trauma to a full bladder. |
Associated with | deep perineal hematoma. | peritonitis, syncopal attack. |
Management | Foley’s/Suprapubic Catheter (SPC) for 7 days. | Laparotomy + Bladder repair in 2 layers + Foley’s/SPC. |
Renal Mass
Differentiating renal mass in an adult on CT

- Macroscopic fat indicates Angiomyolipoma.
- No fat and no enhancement indicates Cyst.
- No fat with enhancement indicates Renal cell carcinoma or other.
Renal cyst
Angiomyolipoma
- Features:
- Type of Hamartoma
- Benign,
- common in 5th-6th decade,
- origin from perivascular epitheloid cells (EPC).
- Neovascular tumor
- Only condition where fat is seen in kidney
- A/w Tuberous sclerosis complex (TSC).
- Clinical Features:
- Usually asymptomatic.
CECT (IOC)
- Fat → looks dirty black on CT.
- B/L angiomyolipomas
- A/w tuberous sclerosis.


Renal cell carcinoma
- CECT (IOC).
- Solid enhancing lesion.
- Clear cell carcinoma is the most common.
- It is hyper-enhancing.

Renal Cystic Lesions
- Includes:
- Autosomal dominant polycystic kidney disease (ADPKD).
- Autosomal recessive polycystic kidney disease (ARPKD).
- Multicystic dysplastic kidney.
Xray


ADPKD
- On CT scan (Image 1), white bone is observed.
- Both kidneys are enlarged in size and have multiple cysts.
- On MRI (Image 2), black bone is observed.
- Both enlarged kidneys have multiple cysts.
- In IVP, initial or nephrogram phase:
- Multiple cysts do not take up the contrast,
- forming filling defects in the kidney.
- Spider leg appearance.
- d/t Splayed collecting system

- Swiss cheese appearance
- On nephrogram

ARPKD
- Striated appearance or sunray appearance of the kidneys.
- The kidney appears echogenic on ultrasonography.
Renal Vascular Pathology
Renal artery stenosis


- Affects the ostium.
- Young patient (without a family history of hypertension)
- 1st investigation is renal Doppler (Image 1)
- has a slow and blunted uptake.
- i.e. pulsus parvus et tardus waveform (Image 2)
- Normal renal artery has a quick upstroke.
- 2nd investigation is CT-angiography or MR-angiography.
- Gold standard procedure is digital subtraction angiography (DSA).
Fibromuscular dysplasia
- Beaded appearance.
- Seen in an MR-angiography.
- Indicates multiple strictures in the renal artery.
- Common in young adult females.
- Also presents with hypertension (similar to renal artery stenosis).

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Adrenal Lesions
- In CT scans, the adrenal gland is seen as an inverted Y-shape or V-shape.
- On the right side, it lies behind the inferior vena cava.
Adrenal adenoma
- The most common incidental adrenal lesion detected.
- Features:
- Fat-containing.
- Rapid wash-in and rapid wash-out of the contrast.
- Hounsfield unit (HU)
- Negative or <10 is considered → adrenal adenoma.
- If > 10 → take a delayed scan → shows ↑sed washout, s/o
- Low lipid Adrenal adenoma

Pheochromocytoma
- Lightbulb sign on T2 weighted MRI (T2W MRI).
- hyperintense in T2ZW MRI


- BIOPSY/FNAC → Contraindicated
Category | Investigation | Notes |
Screening Test/ Initial | 24-hour urine fractionated metanephrine. >> 24 hr urine VMA | Sensitivity and specificity: 98%. |
Confirm → IOC/ Best investigation | Serum plasma free metanephrines | Most sensitive test 100% sensitivity. |
Best / Radiological IOC | MRI abdomen. | Shows light bulb sign |
IOC for Extra-adrenal Pheo | Gallium dotatate (DOTANOC) PET scan scan → detect somatostatin receptors / Tc 99 Dopa PET | Best for detecting metastasis/extra-adrenal sites |
FOR METS | (Nucleotide scan) Metaiodobenzylguanidine (MIBG) scintigraphy | ă…¤ |
Localise Extra adrenal Pheo or mets | Radeon | ă…¤ |




