Inclusion Bodies

Inclusion bodies

Intracytoplasmic Inclusion Bodies:

• Henderson Patterson bodies.
• Positive for: Phloxine tartrate stain.
• Molluscum contagiosum
• Present with: Umbilicated lesions.
• When pressed: Curdy material is extruded.
• Microscopy: Cup-shaped structure.

• Halberstadter Prowazeki bodies:
• Trachoma
• Mnemonic: Trackil odan Horse Power venam

• Levinthal Cole Lillie body:
• C. Psittaci
• Mnemonic: Levinthikkole Lillye sit aaki

• Negri Body:
• Intracytoplasmic eosinophilic inclusion body
• Seen in: Rabies.
• Sellers stain
• Seen after death
• First site: AMMON horn of hippocampus
• Rabies - Hippoptamus
• Sell (Sellers) Nigro (Negri)
• Second site: Cerebellum

Intranuclear Inclusion Bodies:

• Cowdry type A
• Seen in:
• Yellow fever: Torres bodies.
• Herpes Simplex: Lipschultz.
• Mnemonic: Tore Yellow shirt → Kiss Her Lips

• Cowdry type B
• Seen in:
• Adenovirus.
• Poliovirus.
• Mnemonic: Adipoli breast

Both intracytoplasmic + intranuclear forms:

• CMV (Cytomegalovirus)
• Shows: Owl eye appearance.

• Measles
• Shows: Warthin Finkeldey giant cells.
• large grapelike clusters