Insulin Resistance (IR) in Pregnancy😍

Insulin Resistance (IR) in Pregnancy

  • Pregnancy: Diabetogenic state
  • Insulin secretion: decreases glycosuria
  • Hormones causing IR:
    • HPL (main):
      • Detected by 3 weeks POG,
      • maximum by 36 weeks POG
    • Estrogen
    • Progesterone
    • Cortisol
    • hCB: Insulin resistance
  • Note:
    • Physiological edema
      • Oncotic pressure decreases, fluid retention of 4-5 litres: