Globin Chain Production

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  • Alpha-globin chain (Pink curve):
  • Gamma-globin chain (Orange curve):
  • Beta-globin chain (Green curve):
  • Delta-globin chain (Blue curve):
  • Epsilon-globin chain (Black curve):

Globin Chain Production

  • Globin chain synthesis shows a distinct shift from fetal to adult life.
  • Alpha-globin chain (Pink curve):
    • Maintains high production throughout fetal and post-natal life.
  • Gamma-globin chain (Orange curve):
    • Predominantly produced during fetal development.
    • Production decreases significantly as alpha and beta chain synthesis rises post-birth.
  • Beta-globin chain (Green curve):
    • Low in fetal life.
    • Production increases significantly after birth.
  • Delta-globin chain (Blue curve):
    • Low levels.
    • Production begins and gradually increases post-birth.
  • Epsilon-globin chain (Black curve):
    • Transient and present only in early embryonic life.
    • Production declines rapidly to zero.