White matter😊

White Matter

notion image
notion image
notion image


notion image

Association fibers

Long Association Fibers
Long Association Fibers
  • Connects anteroposteriorly
    • Different lobes in the same hemisphere.
Short Association Fibers
Connects two adjacent gyri
Arcuate fasciculus
Broca's speech area (Area 44 and 45)
⇔
Wernicke's speech area (area 22)
Long Association Fibers
ã…¤
Superior longitudinal fasciculus
Frontal lobe ⇔ occipital lobe
Inferior longitudinal fasciculus
Temporal lobe ⇔ occipital lobe
Cingulum
Surrounds Corpus callosum
Uncinate fasciculus
Broca’s speech area (Area 44 and 45)
⇔
Auditory area (Area 41 and 42)

Commissural fibers

  • Made of white matter fibers.
  • Connects the right and left half of the brain.
      1. Corpus callosum
          • Largest
          • Forms the roof of the lateral ventricle.
      1. Anterior commissure
      1. Posterior commissure
      1. Habenular commissure
      1. Hippocampal commissure

Projection Fibers

  1. Internal capsule
  1. Corona radiata
  1. Fimbria / Tracts
notion image

Corpus callosum

notion image
  • RGB IS (rostrum, genu, body, Ischium, splenium) stored in brain
notion image
Parts
ã…¤
Rostrum (R)
Front part, beak-like.
Genu (G)
Curved anterior part.
Body (B)
Main middle section.
Splenium (S)
Posterior rounded end

Connections

  • Largest commissural fiber
  • Connects the two cerebral hemispheres
  • Develops from lamina terminalis
    • Point where anterior neuropore closes
  • Formation: between 12th to 16–20th weeks of gestation
notion image
notion image
 
ã…¤
Forms
Forceps minor
Anterior wall of anterior horn of lateral ventricle
Forceps major
Superior wall of posterior horn of lateral ventricle
notion image
Part
Connections
Named Fibers
Ventricular Relations
Genu
Frontal lobe
Forceps minor
• Anterior bend of CC
Body
Parietal / Temporal lobe
Tapetum fibers
(laterally)
• Forms Roof of body of lateral ventricle
• Connects Occipital to lower part of temporal lobe
Splenium
Occipital lobe
(striate cortex)
Forceps major
• Thickest part
Fibers form:
•
Bulb of posterior horn
• Elevation on medial wall of posterior horn
  • Tapetum fibers
    • Tapetum fibers lie lateral to posterior horn
    • Tapetum connects to occipital and lower temporal lobes
  • Genu → Frontal → Forceps minor
  • Body → Tapetum → Lateral wall/roof contribution
  • Splenium → Occipital → Forceps major → Bulb of post. horn

Corpus callosum agenesis

  • MRI head:
    • Racing car appearance
      • Prominent dilated posterior horns of lateral ventricles.
  • Seen in
      1. Fetal warfarin syndrome → Disala syndrome
      1. Aicardi syndrome
          • Neurodevelopmental disorder
          • Triad
            • Infantile spasms (early infancy)
            • Agenesis of corpus callosum
            • Eye
              • Chorioretinal lacunae
                • Well-circumscribed
                • Pale retinal lesions
              • Retinal colobomas

In Alcohol Abuse

  • Marchiafava Bignami
    • Widespread demyelination of Corpus callosum
    • March il bigname call cheyth - Callosum

Striate cortex

  • Primary visual cortex
    • Area 17
    • Located in posterior part of calcarine sulcus
    • Lobe: Occipital
    • Heavily myelinated
    • Striate appearance:
      • Striae of Gennasi (also known as striate cortex)
  • Mnemonic: Genz vision brod anu → 17, 18, 19 yr olds
  • Accessory visual areas
    • Area 18 → Secondary visual cortex
    • Area 19 → Tertiary visual cortex

Fornix

notion image
Marked structure
notion image
notion image
Mark B → Fornix
notion image
notion image
notion image
  • Structure: White matter.
  • Two fornices (one on each brain side).
  • Origin:
    • Hippocampus.
  • Termination:
    • Joins mammillary body and thalamus.

Fibers

  • Contains all 3 fiber types:
    • Association fibers >
    • Commissural fibers >
    • Projection fibers
  • Right and left fornix connected by commissural fibers.

Blood Supply:

  • Anterior Cerebral Artery

Location and Relations

notion image
  • Forms:
    • Medial wall of lateral ventricle (with septum pellucidum).
    • Roof of 3rd ventricle (with choroid plexus).
  • Position:
    • notion image

Papez Circuit – (Posterior to anterior)

  • Present in both sides of the brain
  • Connects memory & emotion of limbic system.
      1. Hippocampal formation
        1. ↓ via Fornix
      1. Mammillary bodies
        1. ↓ via Mammillothalamic tract
      1. Anterior nucleus of the thalamus
        1. ↓
      1. Cingulate gyrus
        1. ↓ via Cingulum
      1. Entorhinal cortex
        →
        projects back to hippocampus